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They are transmitted by the bite of an infected animal in its saliva and infections safe extra super levitra 100 mg, once fully manifest cheap extra super levitra 100mg overnight delivery, are always lethal (rabies buy cheap extra super levitra 100mg on line, hydro- phobia). Types 2–7 are restricted to Europe, Asia, Africa, and Australia with their main reservoir in bats. Pre-exposure prophylaxis in the form of dead vaccine is adminis- tered to persons at high risk. The two species occur in the form of tropho- zoites (vegetative stages) and cysts (Figs. The of are cells of variable shape and size (10– 60 m) that usually form a single, broad pseudopod (protrusion of cell mem- brane and cytoplasm) that is often quickly extended in the direction of move- ment. Stained preparations of the genus show a characteristic ring-shaped nucleus with a central nucleolus and chromatin granula on the nuclear membrane. Trophozoites that have penetrated into tissues often contain phagocytosed erythrocytes. At first each cyst contains a uninucleate ameba, with glycogen in vacuoles and the so-called chromidial bodies, which are cigar-shaped. The nucleus divides once to produce the binuclear form and later once again to produce the in- fective tetranuclear cyst (Fig. The cysts are eliminated in the stool of infected persons, either alone or together with trophozoites. Following peroral ingestion of a ma- ture cyst, the tetranuclear ameba is released, divides to produce four or eight uninucleate trophozoites, which then continue to multiply and encyst (Fig. Their potential for invading and destroying tissue is high and is based on the following characteristics and processes: adhesion of trophozoites to in- testinal cells by means of surface lectins, killing of cells with pore-forming peptides (amebapore, types A–C) and dissolution of the extracellular matrix bycysteine proteases. This enables the amebas to penetrate into the intestinal wall, where they multiply and cause pathological changes (necrotic foci, ul- cers, inflammatory reactions) (see below). Characterizing as “apatho- genic” is not entirely accurate, since these organisms can cause slight intest- 9 Protozoa Entamoeba histolytica and Other Intestinal Amebas Fig. Here binuclear cyst with gly- cogen vacuole and cigarshaped chromidial bodies and (4) a tetranuclear cyst. If the tip of the polar tubule penetrates the wall of an enterocyte, the spo- roplasm migrates through the hollow tubule into the host cell. The Micro- spora then reproduce locally in intestinal cells or invade other organs from this site. It is not entirely clear by what mechanisms the Microspora are dissem- inated in the body. In cell cultures, the parasites are able to infect neighboring tissue cells by extruding their polar tubule and injecting the sporoplasm into them. In vitro, Microspora are phagocytosed by macrophages and other host cells (so-called nonprofessional phagocytes: epithelial and endothelial cells, mesenchymal cells). The following list summarizes the diseases caused by the individual species together with some diagnostic information. Current knowledge suggests that humans acquire the infection predominantly from infected persons, whereas transmission of genotypes from animals to man—if it occurs at all—is a rare event. Mainly in the small intestine, in enterocytes at the tips of villi, less fre- quently in the colon as well, in the bile ducts and gallbladder. Symptoms: chronic diarrhea, also with cholangiopathy; asymptomatic infections are known to occur. The spores have four to seven polar tubule windings in a double row (in other species: single row! Mainly in the small intestine, in enterocytes, lamina propria, fibroblasts, macrophages, and endothelial cells, also found disseminated, for instance in bile ducts, airways, and the kidneys. Within host cell located in “chambers,” separated off by septa (hence the earlier name ). Of the three known pathogenic strains, two (rabbit and dog strain) have also been found in humans (= zoonosis). Keratoconjunctivitis, sinusitis, bronchitis, pneumonia, nephritis, urinary tract infection, disseminated infection. Morphologically identical to, differentiation possible based on immunology and molecular biology. The miracidia, which remain viable for about three weeks, produce antigens (proteins, glycoproteins), which are secreted through the eggshell into the tissue and are still present in the egg after the ciliated larva has died off. After antigenic stimulation of T lymphocytes secreted cytokines contribute to pro- duce granulomatous reaction foci (so-called “pseudotubercles”): above all macrophages, neutrophilic and eosinophilic granulocytes, as well as fibro- blasts, aggregate around single eggs or a number of centrally located eggs (Fig. These foci may merge and form a starting point for larger, gran- ulomatous proliferations that protrude into the lumen of the urinary bladder or intestine. The eggs in the tissues die off within about three weeks and are either broken down or they calcify. The granulomas are replaced by connec- tive tissue, producing more and more fibrous changes and scarring. The are differentiated according to the localization of the lesions: Causative agent:. Hematuria (mainly in the final portion of urine), micturition discomfort, hyperemia, increasing fibrosis, 1–2mm nodules, necroses, ulcers and calci- fication of the bladder wall, pyelonephrosis and hydronephrosis, urethral strictures, lesions in the sexual organs. In some endemic areas, an increased incidence of urinary bladder cancer has been associated with the infection. The course of an initial infection is only rarely symp- tomatic (see above: Katayama syndrome), inapparent and subclinical courses being the rule. Manifestations in the chronic phase are restricted almost en- tirely to large intestine with hyperemia, granulomatous nodules, papillomas (“bilharziomas”), ulcerations, hemorrhages, and increasing fibrosis, abdom- inal pain and bloody diarrhea. This fibrotic form is caused by eggs deposited around the branches of the portal vein in the liver (“pipestem” fi- brosis according to Symmers) and results in circulatory anomalies, portal hy- pertension, splenomegaly, ascites, hemorrhages in the digestive tract, and other symptoms. Cutaneous lesions (itching, erythema, urticaria, pa- pules) in humans, caused by (repeated) skin penetration of schistosomatid cercariae parasitizing birds (e. The infection occurs worldwide in freshwater or brackish water and is known as “swimmer’s itch. The cercariae of schistosomes from humans can cause similar, although usually milder, symptoms. The prevalence and intensity of infections rise in en- demic regions in children until the age of about 14, followed by a decline usually also accompanied by reduced egg excretion. This acquired immune status, known as “concomitant immunity,” is characterized by total or partial protection against cercarial infection. However, the schistosomes already es- tablished in the body are not eliminated and may persist for years or even decades. The immune defense is directed against schistosomula that have pene- trated the skin, are a few hours old, and present their own antigens on their surface. Young schistosomula can be killed mainly by eosinophils and macro- phages assisted by specific antibodies to these antigens and/or by comple- ment. By the time the schistosomula reach the lungs they are resistant to such cytotoxic attacks. The explanation for this phenomenon is that the older schistosomula are able to acquire host antigens (e. While penetrating the skin the larvae shed their sheaths and migrate into lymphatic and blood vessels.

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Realize that you’ve always known about your friend’s negative qualities and imperfections generic 100 mg extra super levitra with visa, yet you’ve continued to appreciate your friend trusted extra super levitra 100mg. In the second column 100mg extra super levitra with amex, describe a couple of negative qualities or imperfections that your friend has. Following this exercise, realize that your friends probably have a similar pic- ture of you. Curtis fills in the “Appreciating Flawed Friends” exercise in Table 13-1 while thinking about his buddy Jack. In the respective columns, he writes about Jack’s positive qualities and imperfections. There’s no one that Curtis would rather spend time with, and Jack is the first person he would turn to in a crisis. If your friend filled out the same form on you, no doubt she would write about both wonderful qualities and some less-than-wonderful traits. And yet, your friend wouldn’t suddenly give up the friendship because of your imper- fections. Perhaps even more difficult is finding out how to drop defensive barriers in response to criticism from others. Instead of put- ting up barriers to communication and problem solving, admitting to some flaws brings people closer. Table 13-1 Appreciating Flawed Friends Positive Qualities Negative Qualities and Imperfections Jack is one of the funniest guys I know. Even though he’s smart, sometimes Jack makes stupid decisions, espe- cially about money. Jack will help me anytime I need it, no Jack’s a little overweight, and some- matter what. Connecting with the Here and Now In some ways, language represents the peak of evolutionary development. Language makes us human, gives us art, allows us to express complex ideas, and provides us with the tools for creating solutions to problems. At the same time, language lays the foundation for much of our emotional distress. However, they only feel anxiety when they’re in direct contact with experiences that cause them pain or discomfort. More than a few dog owners have had to drag their dogs through the veterinarian’s door by pulling on the leash with all their might. Oh sure, sometimes dogs look pretty guilty when caught chewing on their master’s shoe. Some anxious people still remember the thank-you note that they forgot to write to Aunt Betty six years ago. Unless a dog has been horribly abused, he usually carries on with contentment, joy, and, of course, quite a bit of sleeping. By contrast, humans worry a lot; they obsess over imagined horrors down the road, and they dwell on their past mistakes. When you bring possible future catastrophes as well as past regrets into the present, you’re essentially using language to disconnect you from real- life experience. Doing so can absolutely ruin your present moments — the time that you actually live your entire life! Consider the following example of Reggie, who dreaded the amount of work that he believed he had to finish within five days. Of course, he agonizes over the possibility of put- ting on a less-than-stellar performance, but most of all, he is concerned about the heavy preparation of papers, briefs, depositions, and petitions that must be completed, and soon. He knows that he’ll be working from dawn to dusk with barely enough time to breathe. The funny thing about it, though, is that after the ordeal was over, he realized that most of those five days turned out to be fairly enjoyable. He worried over the possibility of not completing his tasks, which had noth- ing to do with any of the actual work that he performed. It’s simply our ability to ruin the present with thoughts about the future or past that disturbs us. The next time you obsess over future or past events, tasks, or outcomes, con- sider trying the following: ✓ Stay focused on each moment as it comes to you. Chapter 13: Mindful Acceptance 213 ✓ When you notice disturbing thoughts about the future or the past, try just observing them, notice how interesting it is that your mind spins out thoughts like these, and return to the present moment. The following sections contain specific exercises you can use to keep your mind focused on the present moment. Making contact with the present At this very moment, consider coming into direct contact with experience. If judgments enter your mind as you’re doing the following exercise, observe how your mind spins these out like a reflex. Notice how your body feels and notice your position, whether you’re sitting, standing in a subway, riding a bus, or lying in bed. Feel the sensations in your skin as it makes contact with the chair, the bed, the floor if you’re standing, and so on. Instead of thinking about how jarring they sound, study the nuances in the sounds. More than likely, it can be attributed to one or more of the following: ✓ You may have little experience connecting to the present. Whatever the case, we recommend practicing frequent connection with present-moment experiences. Most anxiety and distress come from thoughts about the future or the past, not what’s happening at this moment. Putting worries about the future to rest Most people tell us that at least 90 percent of what they worry about never happens. Of those worrisome events that do occur, less than 10 percent are as bad as they anticipated. That’s an overabundance of worry and ruined present moments just to anticipate a few unpleasant occurrences. Here’s a way you can quit listening to that occasional stream of worries about future events. Think about how many times you’ve made negative forecasts in the past about some pending event. If you’re not sure, keep a log of your negative predictions and see what percentage pans out. Taking these predictions seriously is rather like listening to a weather reporter on the television who tells you that blizzards, severe cold, and ice storms are forecasted for every day. Ninety percent of the time, the reporter is absolutely wrong, and the weather is sunny and warm. When the reporter gets it almost right, rarely are conditions as bad as Chapter 13: Mindful Acceptance 215 described. You can’t turn the station off, but you can at least take the reports less seriously! Mindfully meditating Above and beyond reducing anxiety, mindful acceptance can improve the quality of your life.

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Its extracts and metabolites are antioxidants Glandular - pertaining to or the nature of the gland purchase extra super levitra 100 mg, treatment of the disease with endocrine glands of their extracts Glaucoma – disease of the eye characterized by an increase in the intra ocular pressure which results in atrophy of the optic nerve and blindness of two general types extra super levitra 100mg free shipping, primary which sets in without known cause effective 100mg extra super levitra, and secondary in which there is an increase in intra-ocular pressure due to other eye diseases, the acute type is accompanied by acute pain, the chronic type has an insidious Gliomas – an onset Glioma – a sarcoma (cancerous) of neurological origin; a neoplasm or tumor composed of neuroglia cells Glossitis – inflammation of the tongue Glutamate – a salt of glutamic acid that functions as the brain’s main excitatory neurotransmitter 411 Glycerol – a trihydric alcohol, present in chemical combination in all fats. It is made commercially by the hydrolysis of fats, especially during the manufacture of soap, and is used extensively as a solvent, a preservative, and an emollient in various skin diseases. The volume of erythrocytes (Red blood cells) packed by centrifuge in a given volume of blood. A substance that assists in or stimulates the production of blood cells Hematotoxicity – pertaining to septicemia or toxicity in the blood Hematuria – blood in the urine, urine may be slightly smokey, reddish or very red Hemianopia – blindness for one-half field of vision in one or both eyes 412 Hemiplegia – paralysis of only one half of the body, a brain lesion involving upper motor neurons and resulting in paralysis of the opposite side of the body Hemodialysis – process by which the blood is filtered through a machine when the body is unable to rid itself of natural body toxins for whatever reason Hemodynamics – a study of the forces involved in circulating blood through the body Hemoglobin – the iron containing pigment of red blood cells that carries oxygen from the lungs to the tissues Hemolytic anemia – pertaining to the breakdown of red blood cells to the point of being anemic Hemoptysis – expectoration (vomiting) of blood arising from hemorrhage of the larynx, trachea, bronchi, or lungs, attack sudden, salty taste, blood frothy, bright red Hemorrhage – abnormal discharge of blood, either external or internal, venous, arterial, or capillary from blood vessels into tissues into or from the body, venous blood is dark red, flow is continuous, arterial blood is bright red, flows in jets, capillary blood is of a reddish color, exudes from tissues Hepatic – pertaining to the liver Hepatitis – inflammation of the liver, virus, toxic origin, it is manifested by jaundice (yellowing of the skin or the whites of the eyes) and in some instances, liver enlargement, fewer and other systemic disorders are usually present Hepatobiliary – a combining word referring to the liver and the bile ducts Hepatocellular – pertaining to the cells of the liver Hepatomegaly – enlargement of the liver Herpes simplex – fever blisters, occurrence of clusters of blisters usually on the face (also may be on the genital area) marked by itching and localized pain, lesions will dry up in 10 - 14 days if left alone Hiatal hernia – protrusion of a portion of the stomach upward through the diaphragm. The condition occurs in about 40% of the population and most people display few, if any, symptoms. The major difficulty in symptomatic patients is gastro esophageal reflux, the backflow of acid contents of the stomach into the esophagus Hirsutism – condition characterized by excessive growth of hair or presence of hair in unusual places Histaminergic/histamine – a substance produced from the amino acid histidine, which causes dilation of blood vessels, increased secretion of acid by the stomach, smooth muscle constriction (in the bronchi), and mucus production, tissue swelling, 413 and itching (during allergic reactions) The release of histamine from mast cells is a major component of hypersensitivity reactions, including asthma Histoplasmosis – a systemic fungal, respiratory disease caused by Histoplasma capsulatum. The reservoir for this fungus is in soil with a high organic content and undisturbed bird droppings, especially that around old chicken houses, caves harboring bats, and starlings, blackbirds, and pigeon roosts. It involves a chemical decomposition in which a substance is split into simpler compounds by the addition or the taking up of the elements of water. This kind of reaction occurs extremely frequently in life processes Hydroxycorticosteroid – a powerful steroid that helps in the inflammation within the body during an episode of illness Hyperammonemia – an excess amount of ammonia in the blood or ammonia toxicity. Ammonia is produced in the intestinal tract by bacterial action Hyperbilirubinemia – an excessive amount of bilirubin in the blood. The condition is seen in any illness causing jaundice (yellowing of the skin or whites of the eyes), including diseases in which the biliary tree is obstructed, and those in which blood formation is ineffective Hypercalcemia – an excessive amount of calcium in the blood. The causes of this condition include primary hyperparathyroidism, Lithium therapy, cancers including solid tumors, Vitamin D intoxication, hyperthyroidism, Vitamin A intoxication, aluminum intoxication and milk-alkali syndrome Hypercapnea – an increased amount of carbon dioxide in the blood. Elevated levels of carbon dioxide in the blood result from inadequate ventilation or from massive mismatches between ventilation and perfusion and the blood. Some of the common symptoms are: dizziness, drowsiness, confusion, tremors, and twitching Hyperchloremia – an increase in the chloride content of the blood. Chloride is the major extracellular anion and contributes too many body functions including the maintenance of osmotic pressure, acid-base balance, muscular activity and the movement of water between fluid compartments. It is a frequent finding in many disease processes such as asthma, metabolic acidosis, pulmonary embolism, and pulmonary 415 edema, and also in anxiety-induced states. One way to do this is to have the patient breathe through only one nostril, with the mouth closed. Having the patient breathe in and out of a paper bag is discouraged, as it leads to hypoxemia. After the acute phase of the hyperventilation has been managed, the underlying cause of the problem must be determined. Hypnotic – pertaining to sleep or hypnosis, an agent which induces sleep or which dulls the senses, drugs which cause insensibility to pain by inhibiting afferent impulses or the central centers of the brain receiving sensory impressions, and thus causing partial or complete unconsciousness Hypochondriac – affected with a morbid interest in health and disease Hypoglycemia – deficiency of sugar in the blood, a condition in which there is a level less than 80, hyper function of the pancreas may cause it or injection of an excessive amount of insulin Hypokalemia – an abnormally low concentration of potassium in the blood Hypokinesia – decreased motor reactions to stimulus Hypomania – hypomania and excitement, with a moderate change in behavior Hyponatremia – a decreased concentration of sodium (salt) in the blood Hypophysis – the pituitary body or gland Hypotension – decrease of systolic and diastolic blood pressure below normal, deficiency in tone or tension, below a blood pressure of 90/50 is pathologic, if increased pressure is followed by decreased pressure can be a serious condition, if the systolic and the diastolic drops proportionately – the patient will respond to the administration of stimulants, hypotension causes an accumulation of blood in the veins and slows down the arterial current Hypothalamic – a portion of the diencephalons compromising the ventral wall of the third ventricle below the hypothalamic sulcus, source of the hormones vasopressin and oxytocin stored and released by the neural lobe of the hypophysis Hypothermia – having a body temperature below normal, an art of lowered body temperature, usually between 78 - 90 degrees, to reduce oxygen need during surgery (especially cardiovascular and neurological procedures) and in hypoxia, to reduce blood pressure and to remedy Hypothyroid – marked by insufficient thyroid secretions in the body resulting in diminished basal metabolism, intolerance of cold temperatures, fatigue, mental apathy, physical sluggishness, constipation, muscle aches, dry skin and hair, and coarsening of features. These symptoms are called myxedema 416 Hypotonia – reduced tension, relaxation of arteries, loss of tone of the muscles or intra-ocular pressure Hypoventilation – reduced rate and depth of breathing Hypovolemia– diminished blood supply Hypoxemia – decreased oxygen tension (concentration) in arterial blood, measured by arterial oxygen partial pressure (PaO2) values. Symptoms may include memory issues, balance, ambulation, depending which area of the brain is affected Infiltrates – to pass into or through a substance or a space. A shadow seen on a chest xray, and assumed to represent blood, pus, or other body fluids in the lung Influenza – an acute contagious respiratory infection marked by fevers, muscle aches, headaches, prostration, cough, and sore throat. The disease usually strikes during the winter Influx – a flowing in 417 Insomnia – chronic inability to sleep or sleep prematurely ended or interrupted by periods of wakefulness, may be caused by a heavy late meal, with some coffee or other stimulants, including sugar in any form, overtiredness, mental fatigue, worry, excitement, and principally the fear of being unable to sleep Interstitial – placed or lying between; pertaining to interstices or spaces within an organ or tissue Intestinal atony – lack of muscle tone in the intestine and failure to contract normally, causing a delay in movement of fecal debris to exit the intestine Intracellular – within the cell Intracerebral – within the cerebellum of the brain. It consists of two lateral hemispheres and a narrow middle portion called the vermis. The cerebellum is involved in synergic control of skeletal muscles and plays an important role in the coordination of voluntary movements. It receives afferent impulses but is not a reflex center in the usual sense; however, it may reinforce some reflexes and inhibit others. Although the cerebellum does not initiate movements, it interrelates with many brainstem structures in executing various movements, including maintaining proper posture and balance; walking and running; fine involuntary movements as required in writing, dressing, eating, and playing musical instruments; and smooth tracking movements of the eyes. The cerebellum controls the property of movement such as speed, acceleration, and trajectory Intra ocular pressure – pressure with in the eyeball Intrathecal – within the spinal canal; within a sheath Involutional - a rolling or turning inward – associated with senile, pre-senile types, and manic-depressive groups Iritis – inflammation of the iris of the eye associated with pain, lacrimation, photophobia, diminution of vision, the iris appears swollen, dull and muddy, and pupil is contracted, irregular and sluggish in reaction Irritable bowel – the way the bowel responds excessively to a stimulus – diarrhea may be increased Ischemia – a temporary deficiency of blood flow to any organ or tissue. The deficiency may be caused by diminished blood flow either through a regional artery or throughout the circulation 418 J Jaundice – a condition characterized by yellowness of the skin, white of eyes, mucous membranes and body fluids, due to deposition of bile pigments resulting from excess bilirubin in the blood, it may result from obstruction of bile passageways, excessive destruction of red blood cells, or disturbances in functioning of the liver cells K Keratitis – inflammation and ulceration of the cornea, which is usually associated with decreased visual acuity, Eye pain, tearing, and light sensitivity are the most common symptoms Ketogenic diet – diet is high in fat, adequate in protein, and has negligible amounts of carbohydrate. It was created to stimulate some of the metabolic effects of fasting, a state known to decrease seizures in some individuals. They seem to do well for 2 or 3 months, then the seizures begin to start in again. Ketones – normal metabolic products, B-hydroxylbutyric acid and aminoacetic acid, from which acetone may arise spontaneously. The two acids are products of lipid pyruvate metabolism, and are oxidized by the muscles. It is metabolized by bacteria in the colon with the production of organic acids and is used to treat constipation and the encephalopathy that develops in patients with advanced cirrhosis of the liver. The unabsorbed sugar produces diarrhea and the acid pH helps to contain ammonia in the feces Laryngeal edema – swelling of the larynx in the throat Laryngospasm - spasm of the larynx in the throat Lavage – washing out of a cavity, example the eye or the abdomen abdomen Lecithin – any of a group of phospholipids common in plants and animals. They are found in the liver, nerve tissue, semen, and in smaller amounts in bile and blood. They are essential in the metabolism of fats and are used in the processing of foods, pharmaceuticals products, cosmetics, and inks. Deficiency leads to hepatic and renal disorders, high serum cholesterol levels, atherosclerosis, and arteriosclerosis Lennox-Gestaut - blanket term covering a variety of seizures (atonic drop attacks, complex partial, absence, and occasional tonic clonic) associated with significant delay in motor and intellectual development and does not respond well to drugs Lens – a transparent refractory as in the lens of the eye Lethargy – a condition of functional sluggishness, stupor, a state similar to hypnosis, or the first stage of hypnotism Leukocytosis – an increase in the number of leukocytes in the blood. It occurs most commonly in disease processes involving infection, inflammation, trauma, or stress, but it also can result occasionally from the use of some medications Leukopenia – abnormal decrease of white blood cells usually below 5000. A great number of drugs may cause leucopenia, as can failure of the bone marrow Leukorrhea – a white estrogen related scant/moderate odorless physiological vaginal discharge, normally preceding menarche and occurring during ovulation, during pregnancy, and in response to sexual excitement. Some women note an increased discharge related to oral contraceptive or hormone replacement therapy. Chronic cervicitis and vaginal infections are the most common causes of abnormal genital discharge. Signs of infection include increased discharge, change in color and consistency, odor, vulvar irritation, dysuria, and itching Limbic – the edge or border of a part, the margin Lipase – a fat splitting enzyme found in the blood, pancreatic secretion and tissues 420 Liposome – the recycling center of the cell where large molecules are broken down into small molecules to be reused kidney shaped organs of lymphoid tissues that lie at intervals along the lymphatic vessels Lupus Erythematous - tubercular skin disease, acute or subacute circulatory disorders and trauma predispose, reddish brown soft patches, circumscribed with raised edges and depressed centers which are white and scar like when scales drop off, disease spreads slowly, middle life females are predisposing factors. A chronic autoimmune inflammatory disease involving multiple organ systems and marked by periodic acute episodes. The disease is more prevalent is women of childbearing ages Lymphadenopathy – disease of the lymph nodes Lymphocyte – a white blood cell responsible for much of the body’s immune protection. Fewer than 1% are present in the circulating blood; the rest lie in the lymph nodes, spleen, and other lymphoid organs, where they can maximize contact with foreign antigens Lymph nodes – one of thousands of small kidneyed shaped organs of lymphoid tissue that lie at intervals along the lymphatic vessels Lysis – the gradual decline of a fever or disease; the opposite of crisis. The death of cells or microorganisms, caused by antibodies, complement, enzymes, or other substances M Macrocythemia – condition in which erythrocytes are larger than larger, example in folate or vitamin B12 deficiencies Malaise – discomfort, uneasiness, indisposition, often indicative of infection Malassezia – a genus of fungi that infects animals and humans.

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